A selected substance (or group of substances) that is suitable in terms of color reaction, color perception and biocompatibility should be applied to a surface in the dialysate circuit (solution approach A) or outside (solution approach C). A color, substance whose breakthrough through the adsorbent indicates its saturation is also possible (solution approach B). The suitability should be characterized in particular by an unambiguous color reaction that stands out strikingly from the color gradients observed in therapy. For this purpose, the perception of the dialysate coloration is to be improved by applying different color spaces (irradiation with light of certain spectral ranges). Within the framework of the project, these substances and application variants are to be determined, presented in more detail and tested on the basis of laboratory experiments. A preferred variant (functional model) will be tested under conditions close to the application and further developed into a prototype.
OpalPLUS: Development of an indicator to detect adsorber saturation in liver dialysis,
Sub-project: Development of optical indicators
SMART Mat & Surf - OPAL Plus Measurements of adsorber saturation, production of model dialysates, investigation of biocompatibility and sterilizability.